Effects of Cytochalasin B upon Microfilaments Involved in Morphogenesis of Salivary Epithelium
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منابع مشابه
Effects of cytochalasin B on membrane-associated microfilaments in a cell-free system
The mode of action of cytochalasin B was examined in vitro using bile canaliculus-enriched plasma membrane fractions isolated from rat liver. The pericanalicular microfilaments, which are mainly actin filaments and which are normally attached to the canalicular membranes, were dissociated from the membranes by cytochalasin B treatment. A microfilamentous network was found in the supernate of th...
متن کاملThe Effects of Cytochalasin B on the Microfilaments of Baby Hamster Kidney (bhk-21) Cells
Attempts were made to test the motile functions of bundles of microfilaments found in baby hamster kidney (BHK-21) cells, by using cytochalasin B (CB). It was found that individual cells respond differently to the drug. These differential effects are quite obvious in both light and electron microscope preparations. Some cells contain normal bundles of microfilaments even after 24 hr in CB, and ...
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Cytoplasmic microfilaments have recently been implicated as the contractile organelles responsible for some of the changes in cell shapes and in intercellular organization occurring during epithelial morphogenesis in embryonic development (7) . The experiments reported here indicate that strikingly similar coordinated cellular changes can be induced in vitro in monolayers of some established ep...
متن کاملMicrofilaments and cytoplasmic streaming: inhibition of streaming with cytochalasin.
Cytochalasin B reversibly inhibits cytoplasmic streaming in both Nitella and Avena cells. Colchicine, on the other hand, has no effect on streaming in either plant; nor does colchicine prevent the recovery of streaming after cytochalasin is withdrawn. The inhibition of protein synthesis by cycloheximide has no effect on either streaming itself or on the recovery of streaming after cytochalasin ...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1970
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.66.2.360